Publications

1. The Role of Free Radicals in Autophagy Regulation: Implications for Ageing. Oxid Med Cell Longev. Feb 2018DOI: 10.1155/2018/2450748

2. Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy. Redox Biol. Apr 2018DOI: 10.1016/j.redox.2017.10.010.

3. Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach. Pharmacol Rev. April 2018DOI: 10.1124/pr.117.014753

4. Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A. Autophagy. Jul 2018. DOI: 10.1080/15548627.2018.1474992

5. Neurogenic and neuroprotective donepezil – flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer’s disease. Eur. J. Med. Chem. Aug 2018DOI: 10.1016/j.ejmech.20168.07.026

6. A role for APP in Wnt signalling links synapse loss with β-amyloid production. Transl Psychiatry. Sep 2018 .    DOI: 10.1038/s41398-018-0231-6

7. Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy. Redox Biol. Sep 2018DOI: 10.1016/j.redox.2018.07.006

8. Multi-target-directed ligands for Alzheimer´s disease: discovery of chromone-based monoamine oxidase/cholinesterase inhibitors. Eur. J. Med. Chem. Oct 2018. DOI: 10.1016/j.ejmech.2018.07.056

9. Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases. Nat Rev Drug Discov. Jan 2019DOI: 10.1038/s41573-018-0008-x

10. New flavonoid – N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties. J. Enzyme Inhib. Med. Chem. Mar 2019. DOI10.1080/14756366.2019.1581184

11. Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties. Eur. J. Med. Chem. Mar 2020. DOI: 10.1016/j.ejmech.2020.112090